Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation

Table 1 Characteristics of participants for Osteopontin enzyme-linked immunosorbent assay

	Cases2	Control3	P-value
Age (yr)	57.24	51.95	0.08171
ALT (IU/L)	36.59	31.41	0.21631
AST (IU/L)	51.45	33.41	0.0180b
GGT (IU/L)	220.76	93.32	0.0121b
INR	1.46	1.04	0.0017d
Albumin (g/L)	35.41	43.55	0.0004f
Bilirubin (μmol/L)	48.38	11.36	0.0065d
EtOH lifetime (kg)	1685	1555	0.99161

Patient characteristics identify cases (drinkers with liver cirrhosis) from controls (drinkers without liver disease) by significant differences in the liver function tests and other biochemical measures of liver injury.

¹Not significant;

²[n = 25 (M); n = 4 (F)]; [n = 17 (M); n = 4 (F)].

^bP < 0.01 vs control;

^dP < 0.001 vs control;

^fP < 0.0001 vs control. INR: International normalised ratio for prothrombin time to predict survival; M: Male; F: Female; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyl transferase.