Is there a role for colon capsule endoscopy beyond colorectal cancer screening? A literature review

Table 1 Performance of colon capsule endoscopy after incomplete colonoscopy

	n	PillCam Colon™ capsule generation	Same day CCE	Colon preparation regiment	Preparation adequacy	Completion of CCE	Complementation of IC	Additional Findings	Study design details
Spada et al[33], 2008	1	First	0	4 L of PEG + NaP boosters	Fair	100%	100%	100%	Case report
Triantafyllou et al[34], 2009	12	First	0	4 L of PEG + NaP boosters	58%	8%	50%	30%	Retrospective
									Case series
Fernández-Urién et al[35], 2011	1	First	0	NR	NR	100%	100%	None	Case report
Pioche et al[37], 2012	107	First	0	1 or 2 L of PEG (MoviPrep®) + NaP boosters	76%	83.20%	NR	33.6%	Prospective cohort study; results are not reported separately for the incomplete colonoscopy cases (n = 77)
Alarcón-Fernández et al[39], 2013	34	First	0	3 L of PEG + NaP boosters	64.70%	77%	85.30%	23.5%	Prospective cohort study
Triantafyllou et al[40], 2014	75	First	33%	1 L of PEG + NaP boosters or 4 L of PEG1	60%	76%	91%	44%	Prospective cohort study
Baltes et al[41], 2013	45	Second	0	PEG (MoviPrep®) + PEG/NaP boosters	70%	80%	87%	18%	Prospective cohort study (preliminary data)
Spada et al[42], 2013	50	Second	0	4 L of PEG	83%	NR	98%	14%	Prospective cohort study (preliminary data); compares CCE-CTC
Nogales et al[43], 2013	96	Second	NR	NR	NR	72%	93%	58%	Prospective cohort study
Negreanu et al[44], 2014	3	Second	0	4 L of PEG + PEG boosters	NR	NR	100%	100%	Case series

¹Depending on the timing of the procedure. IC: Incomplete colonoscopy; NR: Not reported; PEG: Polyethylene glycol solution; MoviPrep^®: Trade mark of a lower-dose polyethylene glycol based solution; NaP: Sodium phosphate; CCE: Colon capsule endoscopy; CTC: Computed tomography colonography.