Hematologic manifestations of Helicobacter pylori infection

Table 3 Association between immune thrombocytopenia and Helicobacter pylori infection in children n (%)

Ref.	Year	Country	Patients with ITP	H. pylori-infected ITP patients	Treated patients	H. pylori-eradicated patients	Patients with platelet response
Rajantie et al[200]	2003	Finland	17	9 (52.9)	9	9 (100)	5 (55.6)
Neefjes et al[201]	2007	Netherlands	47	3 (6.4)	3	3 (100)	3 (100)
Ferrara et al[202]	2009	Italy	24	8 (33.3)	8	8 (100)	8 (100)
Russo et al[203]	2011	Italy	244	50 (20.5)	37	33 (89.2)	13 (39.4)
Subtotal European continent			332	70 (21.1)	57	53 (93.0)	29 (54.7)
Jaing et al[197]	2003	Taiwan	22	9 (40.9)	9	9 (100)	5 (55.6)
Hayashi et al[198]	2005	Japan	10	2 (20.0)	2	1 (50.0)	1 (100)
Hamidieh et al[199]	2008	Iran	31	4 (12.9)	4	4 (100)	1 (25.0)
Subtotal Asian continent			63	15 (23.8)	15	14 (93.3)	7 (50.0)
Total worldwide			395	85 (21.5)	72	67 (93.1)	36 (53.7)

H. pylori: Helicobacter pylori; ITP: Immune thrombocytopenic purpura.