Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice

Figure 2 Expression of Cd68, Cd3e, Ptprc, and Vill in the colonic epithelial cells of male Balb/c mice. Cd68, Cd3e, Ptprc, and Vill were specific cell type markers (Ptprc - a hematopoietic cell marker, Cd3e - a T cell marker, Cd68 - a monocyte/macrophage marker, Vill - an epithelial cells marker). The expression level of genes in the cells was determined by real-time PCR. ^aStatistically significant differences in expression levels of inflammatory cell markers (Cd68, Cd3e, Ptprc) and epithelial cell specific marker Vill in all the experimental groups. Values are presented as mean ± SE. Control group: n = 12. Both DSS-induced colitis groups: n = 8. ^aP < 0.05, both DSS-induced colitis groups vs control. DSS: Dextran sulphate sodium.