Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice

Figure 1 Effect of dextran sulphate sodium treatment on histological parameters in Balb/c mice. Analysis of histological parameters was performed as described in Materials and Methods (original magnification × 10). A: Untreated mice (n = 12); B: Acute dextran sulphate sodium (DSS)-induced colitis group (oral administration of 3.5% DSS solution for 7 d; n = 8); C: Chronic DSS-induced colitis group (oral administration of 3.5% DSS for 44 d; n = 8).