Preoperative differential diagnosis between intrahepatic biliary cystadenoma and cystadenocarcinoma: A single-center experience

Table 2 Preoperative levels of marker proteins

	CEA (ng/mL)	AFP (μg/L)	CA125 (U/mL)	CA19-9 (U/mL)	ALT (U/L)	AST (U/L)	TBIL (μmol/L)	DBIL (μmol/L)
Cystadenoma	1.32 ± 0.72	2.08 ± 1.18	12.51 ± 9.31	22.56 ± 26.30	40.03 ± 61.58	56.07 ± 141.54	19.75 ± 20.32	8.98 ± 16.60
Cystadenocarcinoma	2.02 ± 1.16	3.68 ± 7.02	23.20 ± 21.86	72.55 ± 115.99	30.43 ± 19.43	26.05 ± 14.02	20.02 ± 39.74	10.70 ± 31.14

All the carcinoembryonic antigen (CEA) values in both subgroups were within the normal range: although P = 0.02 between the two groups. There was no statistical significance in the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL) and direct bilirubin (DBIL) before the operation (P > 0.05). However, eight of the 21 patients with cystadenoma and six of the 25 patients with cystadenocarcinoma had remarkable levels of TBIL and DBIL. AFP: Alpha fetoprotein; CA: Carbohydrate antigen.