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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Sep 21, 2014; 20(35): 12581-12587
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12581
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12581
Table 2 Cox proportional hazards model analysis of overall survival
| Variable | Univariate | Multivariate | ||
| HR (95%CI) | P | HR (95%CI) | P | |
| Child-Pugh grade | ||||
| A | 0.26 (0.13-0.70) | 0.0062a | 0.42 (0.17-1.04) | 0.0594 |
| B | 1.00 | 1.00 | ||
| Major HCC | ||||
| Intrahepatic | 1.00 | 1.00 | ||
| Extrahepatic | 0.39 (0.13-0.97) | 0.0430a | 0.57 (0.18-1.52) | 0.2757 |
| Largest tumor | ||||
| < 5 cm | 0.19 (0.07-0.48) | 0.0007a | 0.22 (0.08-0.59) | 0.0030a |
| > 5 cm | 1.00 | 1.00 | ||
| Hand-foot syndrome | ||||
| - | 1.00 | 1.00 | ||
| + | 0.36 (0.15–0.80) | 0.0119a | 0.63 (0.24-1.62) | 0.3481 |
| Hypertension | ||||
| - | 1.00 | 1.00 | ||
| + | 0.40 (0.16-0.93) | 0.0321a | 0.69 (0.24-1.76) | 0.4441 |
| Diarrhea | ||||
| - | 1.00 | |||
| + | 0.61 (0.41-1.36) | 0.4644 | ||
| Alopecia | ||||
| - | 1.00 | |||
| + | 0.49 (0.13-1.36) | 0.1794 | ||
- Citation: Yada M, Masumoto A, Motomura K, Tajiri H, Morita Y, Suzuki H, Senju T, Koyanagi T. Indicators of sorafenib efficacy in patients with advanced hepatocellular carcinoma. World J Gastroenterol 2014; 20(35): 12581-12587
- URL: https://www.wjgnet.com/1007-9327/full/v20/i35/12581.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i35.12581