Extrahepatic immune related manifestations in chronic hepatitis C virus infection

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Sep 21, 2014 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2014; 20(35): 12372-12380
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12372

Table 2 Non organ specific autoreactivity in chronic hepatitis C virus infection[64-68]

Autoantibodies	Prevalence (%)	Clinical significance
Cryoglobulins	40-60	Associated with cryoglobulinemic vasculitis:
		Palpable purpura
		Kidney disease
		Peripheral neuropathy
		Arthritis
ANA	1.6-32	Controversial clinical significance
SMA	6-19.3	Often associated with:
		Patients’ age
LKM-1	0.5-2.5	Fibrosis stage
AMA	0.5-1.4	Disease activity
		No influence on treatment response

ANA: Antinuclear antibodies; SMA: Anti-smooth muscle antibodies; LKM-1: Anti-Liver Kidney Microsomal Antibodies; ΑΜΑ: Antimitochondrial antibodies.

Citation: Tampaki M, Koskinas J. Extrahepatic immune related manifestations in chronic hepatitis C virus infection. World J Gastroenterol 2014; 20(35): 12372-12380
URL: https://www.wjgnet.com/1007-9327/full/v20/i35/12372.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i35.12372