Otilonium bromide in irritable bowel syndrome: A dose-ranging randomized double-blind placebo-controlled trial

Figure 2 Effect of otilonium bromide (20, 40, 80 mg) and placebo on the intensity (A) and frequency (B) of abdominal discomfort, bloating or pain. Data are presented as % change from baseline values. Asterix denotes level of statistical significance (^aP < 0.05) for placebo vs 80 mg otilonium bromide at 1 wk.