Nuclear receptors and pathogenesis of pancreatic cancer

doi:10.3748/wjg.v20.i34.12062

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2014; 20(34): 12062-12081
Published online Sep 14, 2014. doi: 10.3748/wjg.v20.i34.12062

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Figure 7 Nur77 acts as a tumor suppressor and as tumor promoting gene in pancreatic ductal carcinoma, inducing pro-apototic and anti-proliferative genes or repressing pro-survival genes. Dashed lines: Effects yet to be demonstrated in pancreatic ductal adenocarcinoma (PDAC). TRAIL: Tumor necrosis factor-related apoptosis-inducing ligand; PARP: Poly(ADP-ribose) polymerase; RXR: Retinoid X receptor; ER: Endoplasmic reticulum.

Citation: Polvani S, Tarocchi M, Tempesti S, Galli A. Nuclear receptors and pathogenesis of pancreatic cancer. World J Gastroenterol 2014; 20(34): 12062-12081
URL: https://www.wjgnet.com/1007-9327/full/v20/i34/12062.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i34.12062