Abnormal β-catenin immunohistochemical expression as a prognostic factor in gastric cancer: A meta-analysis

Table 3 Meta-analysis of β-catenin expression and clinicopathological features of gastric cancer

Clinicopathological features	Studies (n)	Cases	Pooled OR (95%CI)		P value	Heterogeneity
			Fixed	Random		I2(%)	P value
Lauren classification	17	1793		1.98 (1.19-3.29)	0.009	74	< 0.00001
TNM stage	9	996	1.34 (0.96-1.86)		0.080	44	0.090
The depth of invasion	10	1203		1.48 (0.94-2.33)	0.090	55	0.020
Lymph node metastasis	16	2147		2.00 (1.44-2.77)	< 0.0001	44	0.040
Distant metastasis	4	258	2.69 (1.35-5.38)		0.005	20	0.290
Grade of differentiation	12	1372		2.68 (1.66-4.34)	0.0002	58	0.006
Vascular invasion	3	774	1.11 (0.70-1.76)		0.660	0	0.440

TNM: Tumor-node-metastasis.