Amifostine enhances the antioxidant and hepatoprotective effects of UW and HTK preservation solutions

Table 1 Pathological changes after hepatectomy

Groups	Time	n	SD		CLHC		BD		FC
			(+)	(-)	(+)	(-)	(+)	(-)	(+)	(-)
RL	0 h	8	1	7	2	6	1	7	0	8
	6 h	8	2	6	4	4	2	6	0	8
	12 h	8	5	3	7	1	4	4	1	7
RL + A	0 h	8	2	6	2	6	0	8	0	8
	6 h	8	1	7	0	8	2	6	0	8
	12 h	8	3	5	4	4	2	6	0	8
HTK	0 h	8	1	7	0	8	0	8	1	7
	6 h	8	4	4	4	4	1	7	0	8
	12 h	8	3	5	4	4	2	6	1	7
HTK + A	0 h	8	0	8	0	8	0	8	0	8
	6 h	8	2	6	1	7	0	8	0	8
	12 h	8	1	7	2	6	1	7	1	7
UW	0 h	8	1	7	0	8	0	8	0	8
	6 h	8	4	4	4	4	0	8	1	7
	12 h	8	3	5	3	5	1	7	1	7
UW + A	0 h	8	0	8	0	8	0	8	0	8
	6 h	8	1	7	1	7	0	8	0	8
	12 h	8	1	7	1	7	0	8	0	8

SD: Sinusoidal dilatation; CLHC: Centrilobular hydropic change; BD: Hepatocyte balooning degeneration; FC: Fatty change; RL + A: Ringer Lactate + amifostine; HTK: Histidine-tryptophan-ketoglutarate; UW: University of Wisconsin.