Heartburn and regurgitation have different impacts on life quality of patients with gastroesophageal reflux disease

Table 3 Basic characteristic of the of non-erosive reflux disease and erosive esophagitis patients in the heartburn and regurgitation group

Characteristics		Heartburn group				P value	Regurgitation group				P value
		NERD (n = 54, 50%)		EE (n = 54, 50%)			NERD (n = 56, 45.2%)		EE (n = 68, 54.8%)
		n (%)	mean ± SD	n (%)	mean ± SD		n (%)	mean ± SD	n (%)	mean ± SD
Mean age (yr)			46.89 ± 14.75		50.56 ± 13.15	0.3401		39.64 ± 10.23		48.21 ± 19.77	0.0431
Gender	M	22 (40.7)		40 (74.1)		0.0132	16 (28.6)		32 (47.1)		0.1372
	F	32 (59.3)		14 (25.9)			40 (71.4)		36 (52.9)
Weight (kg)			56.59 ± 10.07		68.00 ± 14.34	0.0011		60.28 ± 8.71		64.85 ± 13.67	0.1311
BMI (kg/m2)			21.68 ± 3.43		24.24 ± 3.92	0.0141		22.59 ± 2.90		23.52 ± 3.65	0.2931
H. pylori		14 (25.9)		14 (25.9)		1.0002	8 (14.3)		14 (20.6)		0.5182
Hiatal hernia		8 (14.8)		22 (40.7)		0.0332	16 (28.6)		18 (26.5)		0.8542
ECJ ulcer		0		8 (14.8)		0.0503	0		12 (17.6)		0.0283

¹t test;

²Pearson’s χ² test;

³Fisher exact test. BMI: Body mass index; ECJ: Esophagocardiac junction; EE: Erosive esophagitis; F: Female; M: Male; NERD: Non-erosive reflux disease; H. pylori: Helicobacter pylori.