Early detection and prevention of pancreatic cancer: Is it really possible today?

Table 6 Surgical procedure performed in patients at ”hereditary risk” for pancreatic cancer (n)

Ref.	Year	Resected	PanIN1	PanIN2	PanIN3	Pancreas cancer	Other bening lesions	Other malignant lesions	Benign IPMN	Malignant or high-grade displasia IPMN	Malignant lesions or high-grade dysplasia1
Brentnall et al[106]	2006	7	-	2	2	-		-	2	1	42.8%
Poley et al[108]	2009	3	-	-	-	3		-	-	-	100%
Verna et al[110]	2010	5	-	-	-	1	-	-	4	-	20%
Ludwig et al[111]	2011	6	1	1	1	1	-	-	2	-	16.7%
Vasen et al[112]	2011	7	-	-	-	7	-	-	-	-	100%
Al-Sukhni et al[113]	2011	4	-	-	-	1	-	1	2	-	50%
Schneider et al[114]	2011	9	1	1	1	1	3	-	2	-	22.2%
Canto et al[115]	2012	5	-	-	1	-	-	-	3	1	40%
Total		46	2	4	5	14	3	1	15	2	47.8%

¹The percentage refers to all resected patients, not to all patients included in the study. IPMN: Intraductal papillary mucinous neoplasm; PanIN: Pancreatic intraepithelial neoplasia.