S-1-based vs non-S-1-based chemotherapy in advanced gastric cancer: A meta-analysis

Table 3 Comparison of objective response rate, overall survival, progression-free survival and time-to-treatment failure between S-1-based chemotherapy and 5-FU-based or capecitabine-based chemotherapy

Subgroups	ORR		OS		PFS		TTF
	RR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
S-1 vs 5-FU	1.454 (1.038-2.036)	0.029	0.895 (0.805-0.995)	0.041	0.809 (0.635-1.030)	0.086	0.832 (0.751-0.992)	0
S-1 vs capecitabine	0.952 (0.649-1.397)	0.801	1.090 (0.803-1.481)	0.579	1.036 (0.764-1.405)	0.819	Not applicable	Not applicable

ORR: Objective response rate; OS: Overall survival; PFS: Progression-free survival; TTF: Time-to-treatment failure; 5-FU: 5-fluorouracil.