Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy

doi:10.3748/wjg.v20.i33.11871

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 33

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6016)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-4) series, Tables (1-4) series.

Item

Count

PDF

435

WORD

196

HTML

3212

Figures (1-4)

207

Tables (1-4)

174

Sum=4224

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

953

Download

839

Sum=1792

Sep 7, 2014 (publication date) through Nov 5, 2024

Times Cited of This Article

Times Cited (25)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastroenterol. Sep 7, 2014; 20(33): 11871-11877
Published online Sep 7, 2014. doi: 10.3748/wjg.v20.i33.11871

Table 3 Patient parameters in patients with or without liver dysfunction after major liver resection

Parameters	Liver dysfunction (n = 135)	No Liver dysfunction (n = 430)	OR (95%CI)	P value
Male	127 (94.1)	357 (83.0)	2.87 (1.42-5.79)	0.001
Age > 65 yr	12 (8.9)	62 (14.4)	0.58 (0.30-1.11)	0.097
Preoperative platelet < 100 × 10⁹/L	37 (27.4)	70 (16.3)	1.94 (1.23-3.07)	0.004
Postoperative platelet < 100 × 10⁹/L	46 (34.1)	100 (23.3)	1.71 (1.12-2.60)	0.012
BMI (kg/m²), mean (SD)	22.9 (21.2-25.0)	22.5 (20.9-24.5)	Not available	0.147
Esophageal varices	36 (26.7)	33 (7.7)	4.38 (2.60-7.37)	0.001
Hypertension	22 (16.3)	74 (17.2)	0.94 (0.56-1.58)	0.805
Cardiovascular disease	4 (3.0)	11 (2.6)	1.16 (0.36-3.71)	0.799
Pulmonary disease	2 (1.5)	10 (2.3)	0.63 (0.14-2.92)	0.802
Diabetes mellitus	10 (7.4)	38 (8.8)	0.83 (0.4-1.70)	0.603
ASA III-IV	17 (12.6)	62 (14.4)	0.86 (0.48-1.52)	0.594
HBsAg	119 (88.1)	335 (77.9)	2.11 (1.19-3.73)	0.009
HBeAg	24 (17.8)	56 (13.0)	1.44 (0.86-2.44)	0.167
HBV DNA > 2000 U/mL	47 (34.8)	139 (32.3)	1.12 (0.74-1.68)	0.591
AST (U/L) > ULN	75 (55.6)	187 (43.5)	1.62 (1.1-2.40)	0.014
ALT (U/L) > ULN	55 (40.7)	127 (29.5)	1.64 (1.10-2.50)	0.015
Total bilirubin (μmol/L), median (IQR)	16.1 (11.4-20.5)	12.5 (9.6-17.4)	Not available	< 0.001
Hemoglobin (g/L), median (IQR)	146 (131-157)	139 (127-150)	Not available	0.001
Liver volume removed				< 0.001
< 35%	15 (11.1)	145 (33.7)	1 (reference)
35%-65%	32 (23.7)	97 (22.6)	3.19 (1.64-6.20)
> 65%	88 (65.2)	188 (43.7)	4.53 (2.51-8.15)
Extrahepatic procedures	37 (27.4)	86 (20.0)	1.51 (0.97-2.36)	0.069
Liver resection with				0.248
Hooking with ligation	38 (28.1)	100 (23.3)	1.29 (0.84-2.0)
Ultrasonic dissection	97 (71.9)	330 (76.7)	0.77 (0.5-1.20)
Inﬂow occlusion	54 (40.0)	197 (45.8)	1.27 (0.86-1.88)	0.236
Anatomic resection	98 (72.6)	289 (67.2)	1.29 (0.84-1.98)	0.240
Blood loss (mL), mean (SD)	770 (1049)	585 (433.0)	Not available	0.003
PRBCs transfusion	47 (34.8)	116 (27.0)	1.45 (0.96-2.19)	0.080
Hospital stay (d), median (IQR)	14 (11-19)	13 (11-16)	Not available	0.001

BMI: Body mass index; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; SD: Standard deviation; ULN: Upper limit of normal; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; IQR: Interquartile range.

Citation: Wang HQ, Yang J, Yang JY, Wang WT, Yan LN. Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy. World J Gastroenterol 2014; 20(33): 11871-11877
URL: https://www.wjgnet.com/1007-9327/full/v20/i33/11871.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i33.11871