Bovine immunoglobulin protein isolates for the nutritional management of enteropathy

Table 1 Weight gain and growth following dietary supplementation with plasma protein concentrates

Animal Model (age)	Impact of dietary supplementation with SBI	Ref.
Piglets: 14-21 d	Superior growth and feed intakes during the first week in 4 of 5 experiments	Pierce et al[28]
	Growth performance improved by the IgG-rich fraction
Piglets: Varying age groups	Consistent improvement in growth, feed intake and sometimes feed conversion; similar results with spray dried plasma from porcine, bovine, and mixed origin	Torrallardona et al[30]
Piglets: Weaned at 14 d	Significantly increased mean daily body weight gains and food conversion efficiencies; no difference in protein intake	Jiang et al[37]
	Significantly greater lean body mass and total carcass mass (P < 0.05)
	Significantly lower circulating urea concentrations (P < 0.05), indicating greater retention of nitrogen and reduced amino acid catabolism
Piglets: Weaned at 21 d, infected with ETEC K88	Increased average daily weight gain and food intake	Bosi et al[44]
	Protected against E. coli-induced inflammation

SBI: Serum-derived immunoglobulin/protein isolates; E. coli: Escherichia coli; ETEC K88: Enterotoxigenic E. coli, K88 strain.