Clinical characteristics and treatment of inflammatory bowel disease: A comparison of Eastern and Western perspectives

Table 1 Clinical characteristics of inflammatory bowel disease in Asian and Western countries

Differences	Asian characteristics
Peak age at disease onset	Smaller second peak
Sex distribution of CD	Male predominance
Cigarette smoking in CD	Lower prevalence
CD distribution and behavior	Ileocolonic predominance
	Similar behavior
UC distribution and behavior	Similar distribution
	Milder disease course
Familial aggregation in IBD	Lower prevalence
Extraintestinal disease	Lower prevalence
Medical treatments	Lower use of thiopurine and anti-TNF therapy
Surgical treatments	Comparable in CD
	Lower in UC
UC-associated CRC	Comparable cumulative risk

CD: Crohn’s disease; UC: Ulcerative colitis; anti-TNF therapy: anti-Tumor necrosis factor therapy; CRC: Colorectal cancer.