MicroRNA-218 is upregulated in gastric cancer after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy and increases chemosensitivity to cisplatin

Figure 3 Upregulation of miR-218 inhibited growth of gastric cancers. A: The upregulation of miR-218 inhibited SGC7901 (human gastric cancer cells) cell growth. Cell viability was measured using a WST-1 kit at indicated time points. Data are presented as mean ± SD from three independent experiments performed in sextuple; B: miR-218 overexpression reduced colony formation of SGC7901 cells. 103 cells were mixed with agarose and seeded in 9-well plates for two weeks; C: The expression levels of miR-218 in the parental SGC7901 and the SGC7901/miR-218 stable cell line. Data are presented as mean ± SD. ^aP < 0.05 vs control.