Complex role for the immune system in initiation and progression of pancreatic cancer

doi:10.3748/wjg.v20.i32.11160

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2014; 20(32): 11160-11181
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11160

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Figure 3 Cytokine signaling in the pancreatic epithelium. In response to damage or disease, the pancreatic epithelial cells release cytokines and chemokines. Activated immune cells secrete numerous chemotactic factors in response to, and in addition to, those secreted by the epithelial cells. TNF: Tumor necrosis factor; IL: Interleukin; MDSC: Myeloid-derived suppressor cells; TAM: Tumor-associated macrophage.

Citation: Inman KS, Francis AA, Murray NR. Complex role for the immune system in initiation and progression of pancreatic cancer. World J Gastroenterol 2014; 20(32): 11160-11181
URL: https://www.wjgnet.com/1007-9327/full/v20/i32/11160.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i32.11160