Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility

Table 3 Distribution of MTHFR C677T and A1298C genotypes and alleles frequency in intestinal, diffuse gastric cancer and controls

Ref.	Sample size			Genotypes distribution									Alleles frequency
	Intestinal	Diffuse	Control	Intestinal			Diffuse			Control			Intestinal		Diffuse		Control
				CC	CT	TT	CC	CT	TT	CC	CT	TT	C	T	C	T	C	T
MTHFR C677T polymorphism
Saberi et al[14]	142	80	780	69	59	14	39	34	7	422	308	50	197	87	112	48	1152	408
Galvan-Portillo et al[18]	88	152	454	50		38	113		39	291		163	NA		NA		NA
Gotze et al[19]	53	37	106	21	24	8	18	15	4	41	49	16	66	40	51	23	131	81
Graziano et al[26]	91	71	164	19	47	25	15	39	17	67	68	29	85	97	69	73	202	126

NA: Not available.