Clinical efficacy of tolvaptan for treatment of refractory ascites in liver cirrhosis patients

doi:10.3748/wjg.v20.i32.11400

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Aug 28, 2014 (publication date) through Feb 24, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2014; 20(32): 11400-11405
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11400

Table 3 Summary of the improvement in the urine excretion, ascites and edema after tolvaptan treatment, according to grading criteria, and in the overall improvement n (%)

	n	Significant improvement	Improvement	No improvement
Urine excretion	39	26 (66.7)	9 (23.1)	4 (10.3)
Abdominal circumference	39	19 (48.7)	13 (33.3)	7 (17.9)
Edema (lower extremities)	24	17 (70.8)	5 (20.8)	2 (8.3)
Overall improvement for all patients¹	39	18 (46.2)	17 (43.6)	4 (10.2)
Overall improvement in patients with coexisting hepatocellular carcinoma¹	19	9 (47.4)	7 (36.8)	3 (15.8)
Overall improvement in patients with coexisting hepatorenal syndrome (Type 1)¹	2	0 (0)	0 (0)	2 (100.0)
Overall improvement in patients with coexisting hepatorenal syndrome (Type 2)¹	7	2 (28.6)	5 (71.4)	0 (0)

¹Overall improvement definitions: Significant improvement = grade of A for urine excretion, ascites and edema; Improvement = grade of B for urine excretion and a grade of improvement for ascites or edema; No improvement = grade of C for urine excretion.

Citation: Zhang X, Wang SZ, Zheng JF, Zhao WM, Li P, Fan CL, Li B, Dong PL, Li L, Ding HG. Clinical efficacy of tolvaptan for treatment of refractory ascites in liver cirrhosis patients. World J Gastroenterol 2014; 20(32): 11400-11405
URL: https://www.wjgnet.com/1007-9327/full/v20/i32/11400.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i32.11400