MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer

doi:10.3748/wjg.v20.i32.11199

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2014; 20(32): 11199-11209
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11199

Table 2 MicroRNAs as prognostic and predictive markers for pancreatic cancer

miRNA	Biopsies	FNA	Prognostic	Predictive of treatment efficacy	Ref.
miR-105, miR-127, miR-187, miR-30a-3p, miR-452, miR-518a-2	X (↑)		+		[26]
miR-155, miR-200, miR-203, miR-205	X (↑)		+		[35]
miR-21 (↑), miR-34a (↓), miR-30d (↓)	X		-		[37]
miR-212 (↑), miR-675 (↑), miR-148a (↓), miR-187 (↓), let-7g (↓)	X		-		[38]
miR-146 (↑), miR-205 (↓), miR-7 (↓)	X		-	-	[50]
miR-10b		X (↑)		-	[51,52]
miR-196a	X (↑)		-		[26]
miR-219	X (↑)		-		[36]
miR-200c	X (↑)		+		[36]
miR-21	X (↑)	X (↑)	-	-	[40,41,51]

miRNAs: MicroRNAs; Biopsies: Resected tumors; FNA: Fine needle aspiration; ↑: Upregulated; ↓: Downregulated; +: Good prognosis/response to treatment; -: Bad prognosis/response to treatment.

Citation: Gayral M, Jo S, Hanoun N, Vignolle-Vidoni A, Lulka H, Delpu Y, Meulle A, Dufresne M, Humeau M, Rieu MCD, Bournet B, Sèlves J, Guimbaud R, Carrère N, Buscail L, Torrisani J, Cordelier P. MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer. World J Gastroenterol 2014; 20(32): 11199-11209
URL: https://www.wjgnet.com/1007-9327/full/v20/i32/11199.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i32.11199