MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer

Table 1 MicroRNAs as diagnostic markers for pancreatic cancer

miRNA	Biopsies	FNA	Circulating	Ref.
Let-7a	X (↓)	X (↓)		[33]
miR-34a	X (↓)			[24]
miR-96	X (↓)			[23]
miR-99a			X (↑)	[55]
miR-101	X (↑)			[67]
miR-132	X (↑/↓)			[21,22]
miR-141	X (↓)			[27]
miR-143	X (↑)			[27]
miR-145	X (↑)			[27]
miR-146a	X (↑)			[27]
miR-148a	X (↓)			[27,29]
miR-148b	X (↓)	X (↓)		[27,34]
miR-150	X (↑)			[27]
miR155	X (↑)		X (↑)	[26,27,53,62,67,68]
miR-16			X (↑)	[57]
miR-181a	X (↑)			[26]
miR-181b	X (↑)			[26]
miR-181d	X (↑)			[26]
miR-185			X (↑)	[59]
miR-191			X (↑)	[55,59]
miR-196a	X (↑)	X (↑)	X (↑)	[27,29,32,53,57]
miR-196b	X (↑)			[27,29]
miR-20a			X (↑)	[55,59]
miR-200a			X (↑)	[56]
miR-200b			X (↑)	[56]
miR-203	X (↑)			[28]
miR-210	X (↑)		X (↑)	[29,54]
miR-212	X (↑)			[20]
miR-216	X (↓)			[27]
miR-217	X (↓)	X (↓)		[27,31]
miR-21	X (↑)	X (↑)	X (↑)	[20,26,25,51,53,55,60,64,67-69]
miR-210	X (↑)		X (↑)	[27,53]
miR-221	X (↑)		X (↑)	[20,26,58,69]
miR-222	X (↑)			[20,26,27]
miR-223	X (↑)			[27]
miR-24			X (↑)	[55]
miR-27a-3p			X (↑)	[59]
miR-29c	X (↓)			[27]
miR-30a-3p	X (↓)			[27]
miR-301	X (↑)			[20]
miR-31	X (↑)			[27]
miR-375	X (↓)			[27]
miR-376a	X (↑)			[20]
miR-494	X (↓)			[27]
miR-1290	X (↑)			[61]

miRNAs: MicroRNAs; Biopsies: Resected tumors; FNA: Fine needle aspiration; ↑: Upregulated; ↓: Downregulated.