Post-liver transplant hepatitis C virus recurrence: An unresolved thorny problem

doi:10.3748/wjg.v20.i32.11095

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Aug 28, 2014 (publication date) through Dec 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2014; 20(32): 11095-11115
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11095

Table 1 Summary of the role of each immune cell line in recurrent hepatitis C post-liver transplant

HCV antibodies	No protective role against HCV reinfection	[86]
CD8 T-cells	Correlation with recurrent hepatitis C (RHC)	[71,88]
CD4 T-cells	Protective role against RHC	[89-94]
CD4/CD25 T-cells	Correlation with RHC	[98,99]
Dendritic cells	Defective in case of RHC	[102,103]
NK/NKT-cells	Controversial: defective in case of RHC; damaging role in RHC	[106-109]
Th1/Th2 paradigm	RHC is related to an imbalance towards Th2 prevalence	[98,102,110]

HCV: Hepatitis C virus; NK: Natural killer; NKT: Natural killer T.

Citation: Grassi A, Ballardini G. Post-liver transplant hepatitis C virus recurrence: An unresolved thorny problem. World J Gastroenterol 2014; 20(32): 11095-11115
URL: https://www.wjgnet.com/1007-9327/full/v20/i32/11095.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i32.11095