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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 28, 2014; 20(32): 11033-11053
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11033
Table 1 Factors contributing to fibrosis progression in chronic hepatitis C
Non-modifiableModifiable
Duration of HCV infectionHigh alcohol consumption (≥ 20-50 g/d)
Older age at infectionInsulin resistance
Male sexObesity
Presence of baseline fibrosisMetabolic syndrome
HIV or HBV co-infectionDaily cannabis use
Infection with HCV genotype 3
Gene polymorphisms involved in iron overload/inflammatory pathways
Latin ethnicity