Serum beta 2-microglobulin as a biomarker in inflammatory bowel disease

Table 1 Demographic characteristics and comparison of serum Beta 2 microglobulin levels with other laboratory markers between patients and controls n (%)

	Controls	UC	CD	P value
	n = 30	n = 43	n = 35
Mean age	38.90 ± 11.05	42.72 ± 13.52	38.28 ± 13.15	0.254
Gender (F/M)	18 (60)/12 (40)	17 (40)/26 (60)	19 (54)/16 (46)	0.188
Duration (yr)		5.04 ± 5.81	4.50 ± 3.70	0.729
Inactive/active		14 (33)/29 (67)	12 (34)/23 (66)
		Left type 29 (67)	Ileal type 24 (69)
Disease location		Extensive 14 (33)	Ileocolonic 11 (31)
B2-M	1.71 ± 0.44	2.41 ± 0.87	2.24 ± 1.01	0.002	UC vs C 0.002
					CD vs C 0.033
					UC vs CD 0.642
CRP	0.57 ± 0.83	1.82 ± 2.94	1.59 ± 2.79	0.188
ESR	10.18 ± 11.31	21.21 ± 18.37	22.76 ± 22.81	0.021	UC vs C 0.047
					CD vs C 0.026
					UC vs CD 0.931
WBC (× 103)	7.09 ± 1.75	7.52 ± 2.84	7.48 ± 3.91	0.190
Albumin	4.43 ± 0.24	4.00 ± 0.62	4.05 ± 0.63	0.005	UC vs C 0.006
					CD vs C 0.023
					UC vs CD 0.916

Data are expressed as absolute numbers (percentage), mean ± SD or median (interquartile range). UC : Ulcerative colitis; CD : Crohn Disease; F: Female; M: Male; B2-M: Beta 2 microglobulin; CRP: C reactive protein; WBC: White blood count; C: Control; ESR: Erythrocyte sedimentation rate.