Clinical mycophenolic acid monitoring in liver transplant recipients

Table 3 Receiver operating characteristic analyses of mycophenolic acid exposure and mycophenolate mofetil-related side effects in liver transplant recipients

Ref.		Area under ROC curve	95%CI	Cut-off value	P value
Hao et al[31]	Side effects1
	MPA C0h	0.748	0.619-0.877	2 mg/L	0.001
	MPA AUC0-12h	0.695	0.559-0.831	40 mg.h/L	0.012
	Leukopenia
	MPA C0h	0.670	0.534-0.805	2 mg/L	0.026
Tredger et al[32]	Leukopenia
	MPA C0h	0.780	0.642-0.919	2.25 mg/L	0.003
	MMF dose	0.750	0.662-0.837		0.007
	Infection
	MPA C0h	0.634	0.499-0.770	2.85 mg/L	0.056

¹Side effects include leukopenia, diarrhea and infection. MMF: Mycophenolate mofetil; ROC: Receiver operating characteristic; MPA: Mycophenolic acid.