Changes in nutritional status after liver transplantation

Table 1 Prevalence of muscle depletion in cirrhotic patients and related outcomes

Ref.	Patients (n)	Definition of muscle depletion	Prevalence of muscle depletion	Outcome associated with muscle depletion
Merli et al[5], 1996	1053	Mid Arm Muscle Area < 5thP	26%	Lower survival in Child A and Child B
			38% M; 8% F
Alberino et al[13], 2001	212	Mid Arm Muscle Area < 5thP	25%	Lower survival at 6, 12 and 24 mo
		Mid Arm Muscle Area < 10thP	37%
Alvares-da-Silva et al[14], 2005	50	Hand-Grip Strength 2 SDs below the mean value for the controls	63%	Higher rate of major complications
Campillo et al[15], 2006	396	Mid Arm Muscle Area < 5thP	53.2%	No correlation with in-hospital mortality
			Child Pugh A:
			74.3% M, 22.2% F;
			Child Pugh B:
			68.9% M, 35.2% F;
			Child Pugh C:
			54.7% M, 21.9% F
Peng et al[16], 2007	268	Protein Index < 0.82 or 2 SDs below the mean protein index for the controls	51%	No outcome evaluated
			63% M; 28% F
			Child Pugh A: 72%;
			Child Pugh B: 43%;
			Child Pugh C: 42%
Huisman et al[17], 2011	84	Hand-Grip Strength	67%	Higher risk of complications
		Mid Arm Muscle Circumference	58%
Fernandes et al[20], 2012	129	Mid Arm Muscle Circumference	13.2%	No outcome evaluated
		Hand-Grip Strength 2 SDs below the mean value for the controls	69.3%
Montano-Loza et al[18], 2012	112	Lumbar Skeletal Muscle Mass Index at CT scan ≤ 38.5 cm2/m2 in women and ≤ 52.4 cm2/m2 in men	40%	Increased 3 and 6 mo mortality
			50% M; 18% F
			Child Pugh A: 13%;
			Child Pugh B: 55%;
			Child Pugh C: 32%
Tandon et al[19], 2012	142	Lumbar Skeletal Muscle Mass Index at CT scan ≤ 38.5 cm2/m2 in women and ≤ 52.4 cm2/m2 in men	41%	Increased mortality in cirrhotic patients awaiting liver transplantation
			54% M; 21% F
			Child Pugh A: 0% M, 14% F;
			Child Pugh B: 42% M, 21% F;
			Child Pugh C: 72% M, 23% F
Merli et al[21], 2013	300	Mid Arm Muscle Circumference < 5thP	39%	Higher rate of hepatic encephalopathy

M: Male; F: Female; CT: Computed tomography.