Early viral kinetics during hepatitis C virus genotype 6 treatment according to IL28B polymorphisms

Table 1 Clinical characteristics and single nucleotide polymorphism rs12979860 of the patients according to hepatitis C virus genotypes

Characteristics	Genotype 1	Genotype 3	Genotype 6	P value
	(n = 15)	(n = 16)	(n = 34)
Age (yr)	46.6 ± 12.9	42.8 ± 8.2	41.2 ± 8.4	NS
Sex (male)	53.3%	81.3%	67.6%	NS
BMI (kg/m2)	24.2 ± 12.1	21.3 ± 5.7	23.7 ± 3.7	NS
ALT (U/L)	86.3 ± 57.8	82.6 ± 51.9	62.6 ± 54.5	NS
Log10 HCV RNA (IU/mL)	6.3 ± 0.8	6.0 ± 0.8	6.5 ± 0.8	NS
Liver fibrosis score				NS
Score 0-2	73.3%	66.7%	71.4%
Score 3-4	26.7%	33.3%	28.6%
SNP rs12979860				NS
CC	66.7%	75.0%	82.3%
CT	20.0%	18.8%	11.8%
TT	13.3%	6.2%	5.9%
RVR	46.7%	87.5%	73.5%	0.039
SVR	66.7%	81.3%	76.5%	NS

Data described as mean ± SD or proportions (%). ALT: Alanine aminotransferase; RVR: Rapid virological response; SVR: Sustained virological response; BMI: Body mass index; HCV: Hepatitis C virus; NS: Not significant