Copyright
©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 14, 2014; 20(30): 10537-10544
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10537
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10537
Table 3 Univariate and multivariate Cox regression analyses of prognostic factors in patients with gastric cancer undergoing total gastrectomy
Characteristic | n | 5-yr OS | Univariate analysis | Multivariate analysis | ||
χ2 | Pvalue | HR (95%CI) | Pvalue | |||
Age (yr) | 3.753 | 0.053 | ||||
< 65 | 248 | 44.4 | ||||
≥ 65 | 138 | 37.0 | ||||
Gender | 0.000 | 1.000 | ||||
Female | 127 | 41.7 | ||||
Male | 259 | 41.7 | ||||
Tumor location | 9.998 | 0.019 | ||||
Upper 1/3 | 119 | 35.5 | ||||
Middle 1/3 | 46 | 47.8 | ||||
Lower 1/3 | 175 | 48.6 | ||||
2/3 or more | 461 | 28.3 | ||||
BMI | 11.744 | 0.001 | 1.405 (1.021-1.935) | 0.037 | ||
< 18.5 kg/m2 | 67 | 26.9 | ||||
≥ 18.5 kg/m2 | 319 | 44.8 | ||||
Bleeding | 11.786 | 0.001 | 1.346 (1.018-1.780) | 0.037 | ||
≤ 200 mL | 150 | 51.3 | ||||
> 200 mL | 236 | 35.6 | ||||
Tumor size | 27.632 | < 0.001 | ||||
< 5 cm | 144 | 57.6 | ||||
≥ 5 cm | 242 | 32.2 | ||||
Borrmann type | 1.613 | 0.204 | ||||
I/II | 142 | 46.5 | ||||
III/IV | 244 | 38.9 | ||||
Histology | 4.831 | 0.028 | ||||
Differentiated | 102 | 51.0 | ||||
Undifferentiated | 284 | 38.4 | ||||
Extranodal metastasis | 17.018 | < 0.001 | ||||
Positive | 70 | 45.6 | ||||
Negative | 316 | 24.3 | ||||
Serosal invasion | 30.363 | < 0.001 | 1.736 (1.115-2.703) | 0.015 | ||
Yes | 310 | 69.7 | ||||
No | 76 | 34.8 | ||||
Lymph node metastasis | 131.31 | < 0.001 | 1.685 (1.487-1.908) | < 0.001 | ||
pN0 | 124 | 71.8 | ||||
pN1 | 58 | 46.6 | ||||
pN2 | 83 | 36.1 | ||||
pN3 | 121 | 12.4 | ||||
TNM stage | 78.584 | < 0.001 | ||||
I | 39 | 84.6 | ||||
II | 100 | 63.0 | ||||
III | 247 | 26.3 | ||||
Postoperative complications | 15.175 | < 0.001 | 1.453 (1.079-1.956) | 0.014 | ||
Yes | 83 | 22.9 | ||||
No | 303 | 46.9 | ||||
Chemotherapy | 2.750 | 0.097 | ||||
Yes | 224 | 48.1 | ||||
No | 162 | 37.1 | ||||
PNI | 2.074 (1.581-2.722) | < 0.001 | ||||
High | 245 | 54.1 | 60.703 | < 0.001 | ||
Low | 141 | 21.1 |
- Citation: Jiang N, Deng JY, Ding XW, Ke B, Liu N, Zhang RP, Liang H. Prognostic nutritional index predicts postoperative complications and long-term outcomes of gastric cancer. World J Gastroenterol 2014; 20(30): 10537-10544
- URL: https://www.wjgnet.com/1007-9327/full/v20/i30/10537.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i30.10537