Clinical epidemiology of gastric cancer in Hehuang valley of China: A 10-year epidemiological study of gastric cancer

doi:10.3748/wjg.v20.i30.10486

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

World J Gastroenterol. Aug 14, 2014; 20(30): 10486-10494
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10486

Table 4 Clinical data of patients of different ages and genders n (%)

	Gastric cancer in youth	Gastric cancer in the elderly	P value	Male	Female	P value
	(n = 580)	(n = 1799)	P value	(n = 1868)	(n = 511)	P value
Histological type			< 0.001			< 0.001
Well-differentiated type	22 (3.8)	399 (22.2)		298 (16.0)	123 (24.0)
Moderately differentiated type	433 (74.7)	1202 (66.8)		1289 (69.0)	346 (67.7)
Poorly/undifferentiated type	125 (21.6)	198 (11.0)		281 (15.0)	42 (8.2)
Pathological type			< 0.001			0.050
Adenocarcinoma	520 (89.7)	1717 (95.4)		1747 (93.5)	490 (95.9)
Squamous cell carcinoma	29 (5.0)	25 (1.4)		42 (2.2)	12 (2.3)
Signet-ring cell carcinoma	17 (2.9)	6 (0.3)		19 (1.0)	4 (0.79)
Other	14 (2.4)	51 (2.8)		60 (3.2)	5 (0.98)
Her-2 Expression			< 0.001			< 0.001
Positive	95 (16.4)	71 (3.9)		68 (3.6)	98 (19.2)
Negative	485 (83.6)	1728 (96.1)		1800 (96.4)	413 (80.8)
Early stage¹			0.681			0.026
	0 (0.0)	4 (0.2)		4 (0.2)	0 (0.0)
Type IIa	0 (0.0)	4 (0.2)		3 (0.2)	1 (0.2)
Type IIb	0 (0.0)	9 (0.5)		7 (0.4)	2 (0.4)
Type IIc	1 (0.2)	5 (0.3)		4 (0.2)	2 (0.4)
Type III	2 (0.3)	10 (0.6)		5 (0.3)	7 (1.3)
Advanced stage²			< 0.001			< 0.001
Type I	44 (7.6)	356 (19.8)		255 (13.7)	145 (28.4)
Type II	60 (10.3)	511 (28.4)		484 (25.9)	87 (17.0)
Type III	317 (23.6)	578 (32.1)		679 (36.3)	216 (42.3)
Type IV	156 (26.9)	322 (17.9)		427 (22.9)	51 (10.0)
H. pylori infection			< 0.001			0.816
Positive	390 (67.2)	577 (32.1)		757 (40.5)	210 (41.1)
Negative	190 (32.8)	1222 (67.9)		1111 (59.5)	301 (59.0)
Lauren classification			< 0.001
Intestinal	124 (21.4)	1448 (80.5)		-	-
Nonintestinal	456 (78.6)	351 (19.5)		-	-

¹Early stage classification was in accordance with the Japanese Society of Gastroenterological Endoscopy;

²Advanced stage classification was in accordance with Borrmann type. Gastric cancer in youths refers to patients between 18 and 45 years old; Gastric cancer in the elderly refers patients between 45 and 85 years old. Her-2: Human epidermal growth factor receptor-2; H. pylori: Helicobacter pylori.

Citation: Yan S, Li B, Bai ZZ, Wu JQ, Xie DW, Ma YC, Ma XX, Zhao JH, Guo XJ. Clinical epidemiology of gastric cancer in Hehuang valley of China: A 10-year epidemiological study of gastric cancer. World J Gastroenterol 2014; 20(30): 10486-10494
URL: https://www.wjgnet.com/1007-9327/full/v20/i30/10486.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i30.10486