Clinical epidemiology of gastric cancer in Hehuang valley of China: A 10-year epidemiological study of gastric cancer

Table 2 Clinical data of patients in past and previous 5-year groups n (%)

	Past 5 yr group	Previous 5 yr group	P value		Past 5 yr group	Previous 5 yr group	P value
	(n = 1394)	(n = 985)			(n = 1394)	(n = 985)
Tumor location			< 0.05	Perineural invasion			< 0.05
Upper (U)	467 (33.5)	266 (27.0)		Positive	685 (49.1)	389 (39.5)
Middle (M)	142 (10.2)	94 (9.5)		Negative	709 (50.9)	596 (60.5)
Lower (L)	705 (50.6)	530 (53.8)		Vascular invasion			< 0.05
UML	80 (5.7)	95 (9.6)		Positive	671 (48.1)	375 (38.1)
Tumor classification				Negative	723 (51.9)	610 (61.9)
Early stage1			> 0.05	Her-2 Expression			> 0.05
Type I	3 (0.2)	1 (0.1)		Positive	104 (7.5)	62 (6.3)
Type IIa	2 (0.1)	2 (0.2)		Negative	1290 (92.5)	923 (93.7)
Type IIb	5 (0.4)	5 (0.5)		H. pylori infection			< 0.05
Type IIc	3 (2.0)	3 (0.3)		Positive	610 (43.8)	357 (36.2)
Type III	8 (5.7)	4 (0.4)		Negative	784 (56.2)	628 (63.8)
Advanced stage2			< 0.05	ER Expression			< 0.05
Type I	201 (14.4)	199 (20.2)		Positive	365 (26.2)	45 (4.6)
Type II	365 (26.2)	206 (20.9)		Negative	1029 (73.8)	940 (95.4)
Type III	520 (37.3)	375 (38.1)		PR Expression			< 0.05
Type IV	288 (20.7)	190 (19.3)		Positive	340 (24.4)	39 (4.0)
Pathological type			< 0.05	Negative	1054 (75.6)	946 (96.0)
Adenocarcinoma	1335 (95.8)	902 (91.6)		Lymph node metastasis			< 0.05
Squamous cell carcinoma	38 (2.7)	16 (1.6)		Positive	1250 (90.0)	850 (86.3)
Signet-ring cell carcinoma	9 (0.6)	14 (1.4)		Negative	144 (10.3)	135 (13.7)
Other	12 (0.9)	53 (5.4)
Histological type			< 0.05	Lauren classification			> 0.05
Well-differentiated type	264 (19.0)	157 (15.9)		Intestinal	890 (63.8)	682 (69.2)
Moderately differentiated type	907 (65.1)	728 (73.9)		Nonintestinal	504 (36.2)	303 (30.8)
Poorly/undifferentiated type	223 (16.0)	100 (10.2)

¹Histological type was based on the criteria of World Health Organization;

²Advanced stage classification was in accordance with Borrmann type; Her-2: Human epidermal growth factor receptor-2; H. pylori: Helicobacter pylori; ER: Estrogen receptor; PR: Progesterone receptor. P < 0.05, the previous vs the past year group.