Insulin resistance, adipokine profile and hepatic expression of SOCS-3 gene in chronic hepatitis C

Table 7 Adipokines and hepatitis C virus viremia

	VL≥600000 IU/mL (n= 12)		VL < 600000 IU/mL (n= 19)		Pvalue
	Median (LQ-UQ)	Min-max	Median (LQ-UQ)	Min-max
Age	32 (23-54)	18-61	32.5 (23.5-38)	18-61	P > 0.05
Adiponectin (μg/mL)	6.46 (5.48-8.72)	3.51-18.48	7.42 (5.48-8.75)	3.55-17.93	P > 0.05
Osteopontin (ng/mL)	31.18 (15.52-37.1)	11.57-59.15	26.84 (21.19-33.78)	5.33-54.98	P > 0.05
Leptin (ng/mL)	4.09 (1.59-21.5)	0.77-54.65	5.47 (2.51-13.11)	1.17-17.2	P > 0.05
Resistin (ng/mL)	1.42 (1.03-1.74)	0.73-2.92	1.56 (1.29-1.78)	0.87-2.71	P > 0.05
Omentin (ng/mL)	393.92 (342.46-534.21)	115.7-757.34	381.88 (312.96-497.43)	227.99-735.84	P > 0.05
HOMA	2.01 (1.5-3.99)	0.88-9.67	2.5 (1.25-3.36)	0.78-5.66	P > 0.05
Visfatin (ng/mL)	2.67 (1.17-3.97)	0.53-9.37	2.14 (1.23-3.11)	0.45-9.33	P > 0.05

Serum adipokine concentrations and HOMA-IR index were not found to be related to HCV viremia. VL: Viral load; SOCS-3: Suppressor of cytokine signaling 3: HOMA-IR: Homeostasis model assessment of insulin resistance; HCV: Hepatitis C virus; LQ: Lower quartile; UQ: Upper quartile.