Epidermal growth factor upregulates Skp2/Cks1 and p27kip1 in human extrahepatic cholangiocarcinoma cells

Figure 5 Results of quantitative polymerase chain reaction for S-phase kinase-associated protein 2, Cyclin-dependent kinases regulatory subunit 1, and p27kip1 after the addition of exogenous epidermal growth factor in (A) SNU-1196, (B) SNU-1079, and (C) SNU-245 cells. Data are representative of triplicate experiments. Statistical analyses were performed by one-way ANOVA. ^bP < 0.01 vs control. EGF: Exogenous epidermal growth factor; Skp2: S-phase kinase-associated protein 2; Cks1: Cyclin-dependent kinases regulatory subunit 1.