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World J Gastroenterol. Jan 21, 2014; 20(3): 786-794
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.786
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.786
Table 6 Multivariate analysis of overall survival in 44 patients with hepatocellular carcinoma and cirrhosis treated with sorafenib
| Variable | OS | ||
| HR (95%CI) | Median OS in weeks (range) | P value | |
| ECOG | |||
| 0 | 1 (ref.) | 50.2 (9.3-153.1) | 0.031 |
| 1-2 | 2.36 (1.08-5.16) | 29.0 (2.9-92.6) | |
| Extrahepatic spread | |||
| Absent | 1 (ref.) | 45.9 (8.1-153.1) | 0.059 |
| Present | 2.41 (0.97-6.01) | 19.1 (2.9-83) | |
| Portal thrombosis | |||
| Absent | 1 (ref.) | 45.8 (2.9-153.1) | 0.015 |
| Present | 3.33 (1.27-8.72) | 29.9 (8.1-50) | |
| ALP (U/L) | |||
| ≤ 120 | 1 (ref.) | 45.9 (16.6-153.1) | 0.017 |
| > 120 | 3.13 (1.23-8.00) | 33.2 (2.9-115.4) | |
| AFP (ng/mL) | |||
| ≤ 40 | 1 (ref.) | 52.5 (10.7-153.1) | 0.021 |
| > 40 | 2.33 (1.13-4.78) | 31.0 (2.9-87.4) | |
- Citation: Inghilesi AL, Gallori D, Antonuzzo L, Forte P, Tomcikova D, Arena U, Colagrande S, Pradella S, Fani B, Gianni E, Boni L, Laffi G, Costanzo FD, Marra F. Predictors of survival in patients with established cirrhosis and hepatocellular carcinoma treated with sorafenib. World J Gastroenterol 2014; 20(3): 786-794
- URL: https://www.wjgnet.com/1007-9327/full/v20/i3/786.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i3.786