KISS1 methylation and expression as predictors of disease progression in colorectal cancer patients

Figure 6 Changes in HCT116 cell invasion and migration after 5-Aza-CdR treatment. A: The invasion of untreated HCT116 cells was determined using a Matrigel invasion assay; B: HCT116 cell invasion in one well after treatment with 5-Aza-CdR; C: Cell migration was determined in untreated cells using a migration assay; D: Cell migration after treatment with 5-Aza-CdR; E: HCT116 cell invasion and migration gradually decreased in a time-dependent manner after treatment; F: HCT116 cell invasion and migration gradually declined with increasing concentrations of 5-Aza-CdR. Each bar represents the mean of 3 independent wells. Scale bar, 20 μm. ^aP < 0.05 vs non-treated control.