Aspirin inhibits cell viability and mTOR downstream signaling in gastroenteropancreatic and bronchopulmonary neuroendocrine tumor cells

Figure 7 The effect of aspirin on EGFR and c-MET signaling in neuroendocrine BON1 and NCI-H727 tumor cells. Human pancreatic neuroendocrine BON1 (A) and bronchopulmonary NCI-H727 (B) cells were treated with the indicated concentrations of aspirin for 24 and 48 h. The expression of pMET, MET, pEGFR, EGFR and a β-actin loading control was evaluated using Western blot analysis. A representative blot from 3 independently performed experiments is shown.