Aspirin inhibits cell viability and mTOR downstream signaling in gastroenteropancreatic and bronchopulmonary neuroendocrine tumor cells

Figure 2 Inhibition of neuroendocrine NCI-H727 cell viability by aspirin. Human bronchopulmonary neuroendocrine NCI-H727 cells were treated with the indicated concentrations of aspirin for 72, 144 and 216 h. The viability of the cells was measured based both metabolic activity using the Cell Titer 96 kit (Promega) (A) and DNA labeling experiments using SYBR green (Lonza) (B). The data shown are the mean ± SD of 3 independently performed experiments. ^aP < 0.05, ^bP < 0.01 vs untreated control.