Antimicrobial susceptibility testing for Helicobacter pylori in times of increasing antibiotic resistance

Table 1 Proposed clinical antimicrobial breakpoints for Helicobacter pylori

Antibiotic	Susceptible (mg/L)	Resistant (mg/L)
Amoxicillin	≤ 0.12	> 0.12
Clarithromycin	≤ 0.25	> 0.5
Metronidazole	≤ 8	> 8
Levofloxacin	≤ 1	> 1
Rifampicin1	≤ 1	> 1
Tetracycline	≤ 1	> 1

¹Although rifabutin is used clinically, rifabutin E tests are not available routinely and rifampicin is used to screen for rifabutin resistance. Adapted from European Committee on Antimicrobial Susceptibility Testing[48].