Genetic predisposition to colorectal cancer: Where we stand and future perspectives

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Aug 7, 2014 (publication date) through Feb 14, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2014; 20(29): 9828-9849
Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.9828

Table 5 Clinical characteristics of the PTEN hamartoma tumor syndrome

Clinical characteristics
Benign neoplasia
Dermatologic
Palmoplantar keratoses
Trichilemmomas
Lipomas
Fibromas
Freckling of the glans penis
Vascular anomalies/hemangiomas
Lhermitte-Duclos (dysplastic gangliocytoma of the cerebellum)
Genitourinary tumors/malformations
Colorectal polyposis
Mucosal lesions
Thyroid goiter/nodules
Proliferative breast changes
Malignant neoplasia
Breast cancer
Non-medullary thyroid cancer
Renal cancer
Endometrial cancer
Colorectal cancer
Melanoma
Central nervous system
Macrocephaly
Autism/developmental delay
Dysmorphic characteristics
Dolichocephaly
Postaxial polydactyly

Citation: Valle L. Genetic predisposition to colorectal cancer: Where we stand and future perspectives. World J Gastroenterol 2014; 20(29): 9828-9849
URL: https://www.wjgnet.com/1007-9327/full/v20/i29/9828.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i29.9828