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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 7, 2014; 20(29): 9633-9652
Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.9633
Table 3 Degree of telaprevir and boceprevir resistance associated mutations
Degree of resistanceMutationsFold increase
Low levelV36A/M/C3.5-7
T54A/S6-12
R155K/T/Q8.5-11
IntermediateV36A/M + R155K/T57-71
High levelA156V/T74-410
V36A/M + A156V/T> 700