Clinical outcome of small hepatocellular carcinoma after different treatments: A meta-analysis

Table 2 Characteristics of cases involving percutaneous ethanol injection vs radiofrequency ablation

Ref.	Treatment	M/F	Mean tumor size (cm)	Mean age (yr)	Mean AFP (ng/mL)	Child-Pugh A/B	Mean follow-up (mo)
Brunello et al[21]	PEI	49/30	2.25 ± 0.54	70.3 ± 8.1	16.5 (MD)	39/30	25.3 (MD)
	RFA	43/27	2.42 ± 0.49	69.0 ± 7.7	22.0 (MD)	39/31	26.1 (MD)
Lin et al[22]	PEI	34/18	2.8 ± 0.9	67 ± 6.0	> 400 (n = 8)	39/12	23.8 ± 10.4
	RFA	35/17	2.9 ± 0.8	59 ± 10	> 400 (n = 7)	41/11	24.5 ± 11.3
Shiina et al[23]	PEI	87/27	≤ 2.0 (n = 57)	≤ 65 (n = 41)	> 400 (n = 7)	85/29	2.9 (MD)
	RFA	79/39	≤ 2.0 (n = 45)	≤ 65 (n = 45)	> 400 (n = 6)	85/33	3.1 (MD)
Lin et al[24]	PEI	39/23	2.3 ± 0.8	60 ± 8	400 (n = 9)	47/15	26 ± 12
	RES	30/22	2.5 ± 1.0	61 ± 10	400 (n = 10)	46/46	28 ± 12
Lencioni et al[25]	PEI	30/20	2.8 ± 0.8	69 ± 7.4	54 (MD)	35/15	22.4 ± 8.6
	RFA	36/16	2.8 ± 0.6	67 ± 6.0	57 (MD)	45/7	22.9 ± 9.4

PEI: Percutaneous ethanol injection; RFA: Radiofrequency ablation; M: Male; F: Female; AFP: Alpha-fetoprotein; MD: Median; RES: Resection.