Molecular pathology of intraductal papillary mucinous neoplasms of the pancreas

Table 3 Correlation between mutation of the gene and grade of dysplasia of intraductal papillary mucinous neoplasm

Ref.	Gene	Adenoma	Borderline	Carcinoma in situ	Invasive carcinoma
Wu et al[29], 2011	KRAS2	87%	90.2%	70.7%	70.7%
Dal Molin et al[36], 2013	GNAS	19%	23%	58%	58%
Schönleben et al[41], 2006	PI3KCA	0%	2.7%	2.7%	5.5%
Schönleben et al[22], 2007	BRAF	0%	0%	0%	2.7%
Hashimoto et al[48], 2008	hTERT	15.8%	35.7%	85%	86.7%
Jang et al[50], 2007	Shh	46.2%	35.7%	80%	84.6%
Wada[26], 2002	CDKN2A/p16	12.5%	20%	33%	100%
Abe et al[64], 2007; Wada et al[26], 2002	p53	0%	33.3%	38.5%	100%
Biankin et al[55], 2002	DPC4	0%	0%	38%	75%
Dal Molin et al[81], 2012	BRG1	28%	52%	76%	76%
Jang et al[23], 2009	S100A4	7.4%	7.4%	42.9%	42.9%