Lifetime risk of esophageal adenocarcinoma in patients with Barrett's esophagus

doi:10.3748/wjg.v20.i28.9611

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2014; 20(28): 9611-9617
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9611

Table 2 Development of high-grade dysplasia and adenocarcinoma

Ref.	Number of patients	Incidence of high-grade dysplasia or adenocarcinoma (n/yr follow-up)	Annual incidence of high-grade dysplasia or adenocarcinoma (95%CI)¹	Number of cases expected to develop high-grade dysplasia or adenocarcinoma (95%CI)	Individual’s lifetime risk of developing high-grade dysplasia or adenocarcinoma (95%CI)
Yousef et al[6] 2008	4491	178/22609	0.79% (0.67-0.91)	1379 (1184-1598)	0.175 (0.150-0.203)
Sikkema et al[7] 2010	4528	194/22559	0.86% (0.74-0.99)	1506 (1302-1734)	0.191 (0.165-0.220)
Thomas et al[8] 2007			0.9%	1577	0.200
Gatenby et al[3] 2008	806	39/3908	1.0% (0.71-1.4)	1748 (1243-2390)	0.222 (0.158-0.303)

¹95%CI evaluated using an exact poisson distribution.

Citation: Gatenby P, Caygill C, Wall C, Bhatacharjee S, Ramus J, Watson A, Winslet M. Lifetime risk of esophageal adenocarcinoma in patients with Barrett's esophagus. World J Gastroenterol 2014; 20(28): 9611-9617
URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9611.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9611