Alterations in enterocyte mitochondrial respiratory function and enzyme activities in gastrointestinal dysfunction following brain injury

Table 1 Changes in mitochondrial respiratory function (mean ± SD)

Groups	State 3 respiration	State 4 respiration	RCR	P/O
Control	24.46 ± 1.71	4.33 ± 0.25	5.42 ± 0.46	3.46 ± 0.12
TBI 6 h	23.89 ± 1.85	4.54 ± 0.53	5.20 ± 0.18b	3.42 ± 0.15
TBI 12 h	23.04 ± 2.30	4.21 ± 0.74	4.55 ± 0.35b	3.30 ± 0.10b
TBI 24 h	19.65 ± 1.94	5.42 ± 0.18	3.75 ± 0.22b	2.61 ± 0.21b
TBI 2 d	20.04 ± 2.01	5.05 ± 0.32	4.12 ± 0.53b	2.95 ± 0.18b
TBI 3 d	18.73 ± 1.88	5.27 ± 0.61	3.45 ± 0.41b	2.76 ± 0.09b
TBI 7 d	25.22 ± 1.76	4.36 ± 0.46	5.23 ± 0.24b	3.43 ± 0.11

^bP < 0.01 vs control. TBI: Traumatic brain injury; RCR: Respiratory control ratio; P/O: ADP/O ratio.