Osteoporosis and fractures in liver disease: Relevance, pathogenesis and therapeutic implications

doi:10.3748/wjg.v20.i28.9427

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Jul 28, 2014 (publication date) through Aug 2, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2014; 20(28): 9427-9438
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9427

Table 3 Factors implicated in inducing bone loss in liver disease

Fibronectin (plasma and oncofetal forms)

IGF-I

RANKL/OPG

IL-6

Sex hormones

Bilirubin

Vitamin D metabolism

Corticosteroid therapy

IGF-I: Insulin like growth factor-I; IL: Interleukin; OPG: Osteoprotegerin; RANKL: Receptor-activator of nuclear factor kappa ligand.

Citation: Nakchbandi IA. Osteoporosis and fractures in liver disease: Relevance, pathogenesis and therapeutic implications. World J Gastroenterol 2014; 20(28): 9427-9438
URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9427.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9427