Atypical causes of cholestasis

doi:10.3748/wjg.v20.i28.9418

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2014; 20(28): 9418-9426
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9418

Table 2 Common causes of drug-induced liver injury in the United States

Types of drugs	Specific drugs (number of cases)
Analgesics/NSAIDs	Acetaminophen (124)
	Drugs in combination with APAP (3)
	Diclofenac (4)
	Celecoxib (2)
Antimicrobials	Isoniazid (37)
	Amoxicillin/clavulanate (24)
	Nitrofurantoin (13)
	Trimethoprim/sulfamethoxazole (9)
	Ciprofloxacin (5)
	Levofloxacin (4)
	Terbinafine (4)
	Telithromycin (5)
	Fialuridine (3)¹
	Azithromycin (3)
	Oxacillin (3)
	Minocycline (3)
	Amoxicillin (2)
	Doxycycline (2)
	Fluconazole (2)
	Nevirapine (2)
CNS Agents	Valproate (16)
	Phenytoin (15)
	Methyldopa (8)
	Lamotrigine (5)
	Duloxetine (6)
	Atomoxetine (3)
	Fluoxetine (2)
	Nefazodone (2)1
	Buproprion (2)
Anti-inflammatory/Immunologics	Interferon beta (6)
	Sulfasalazine (3)
	Etanercept (3)
	Mercaptopurine (3)
	Antithymocyte globulin (2)
Endocrine	Propylthiouracil (13)
Endocrine	Troglitazone (4)¹
Statins	Atorvastatin (3)
Statins	Cerivastatin (2)¹
Anesthetics	Halothane (3)
Anesthetics	Desflurane (2)
Cardiovascular	Labetolol (2)
Cardiovascular	Amiodarone (2)
Others	Disulfiram (6)
	Allopurinol (2)
	Ranitidine (2)

¹Discontinued or non-FDA approved drugs. APAP: Acetaminophen; NSAIDs: Non-steroidal anti-inflammatory drugs; CNS: Central nervous system; FDA: Food and drug administration. Adapted From: Russo et al[90] and Chalasani et al[80].

Citation: Nguyen KD, Sundaram V, Ayoub WS. Atypical causes of cholestasis. World J Gastroenterol 2014; 20(28): 9418-9426
URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9418.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9418