Familial colorectal cancer: A review

Table 2 Screening guidelines in familial colorectal cancer

	ACG[6]	ASGE[7]	USMTF[8]
First degree relative with CRC diagnosed at age < 60 or two or more first degree relatives	Colonoscopy at age 40 or 10 yr younger than affected relative; if normal repeat every 5 yr	Colonoscopy at age 40 or 10 yr younger than affected relative; if normal repeat every 5 yr	Colonoscopy at age 40 or 10 yr younger than affected relative; if normal repeat every 5 yr
First degree relative with CRC diagnosed at ≥ 60	Same as average risk	Colonoscopy at age 40 or 10 yr younger than affected relative; if normal repeat every 10 yr	Screening should be at an earlier age (40); individuals may choose to be screened with any recommended form of testing
Second- or third-degree relatives with CRC	-	As average risk individuals	-

CRC: Colorectal cancer; ASGE: American Society for Gastrointestinal Endoscopy; ASG: American College of Gastroenterology; USMTF: US Multi-Society Task Force.