Update on the prevention of local recurrence and peritoneal metastases in patients with colorectal cancer

Table 1 National Institutes of Health randomized study: Long-term intraperitoneal 5-fluorouracil can prevent the occurrence of peritoneal metastases n (%)

	Sites of treatment failure for IV or IP 5-FU
	No. of patients	No. of recurrences	Peritoneal surface	Liver
IP 5-FU	36	13 (36)	2/10	3/11
IV 5-FU	30	11 (37)	10/11	4/11
Statistical analysis P2			0.003	1.000

From ref. [11] with permission. 5-FU: 5-fluorouracil.